Structure and distribution of the phosphoprotein phosphatase genes, prpA and prpB, among Shigella subgroups.

@article{Li2005StructureAD,
  title={Structure and distribution of the phosphoprotein phosphatase genes, prpA and prpB, among Shigella subgroups.},
  author={Baoguang Li and Eric W. Brown and Christine D'Agostino and Joseph E Leclerc and Thomas A. Cebula},
  journal={Microbiology},
  year={2005},
  volume={151 Pt 8},
  pages={2671-83}
}
Phosphoprotein phosphatases encoded by the prpA and prpB genes function in signal transduction pathways for degradation of misfolded proteins in the extracytoplasmic compartments of Escherichia coli. In order to trace the evolution of prp genes and assess their roles in other enteric pathogens, the structure and distribution of these genes among closely related Shigella subgroups were studied. PCR amplification, probe hybridization studies and DNA sequencing were used to determine the prp… CONTINUE READING

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