Structure and developmentally regulated expression of a Strongylocentrotus purpuratus collagen gene.

@article{Venkatesan1986StructureAD,
  title={Structure and developmentally regulated expression of a Strongylocentrotus purpuratus collagen gene.},
  author={Meera Venkatesan and Flora de Pablo and Gabriel Vogeli and R. T. Simpson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1986},
  volume={83 10},
  pages={3351-5}
}
We have isolated and partially characterized an ca. 20-kilobase-pair Strongylocentrotus purpuratus genomic clone, using a mouse alpha 1 (type IV) collagen cDNA probe. A 1-kilobase-pair HindIII fragment of the clone hybridizes strongly to the probe; this has been subcloned and sequenced. It contains 212 base pairs of sequence coding for (Gly-Xaa-Yaa)n (where Xaa and Yaa are different unspecified amino acids), characteristic of all known collagen genes. There is a single point of discontinuity… CONTINUE READING