Structure and Properties of a Novel Neutrophil-Activating Factor (NAF) Produced by Human Monocytes

@inproceedings{Walz1989StructureAP,
  title={Structure and Properties of a Novel Neutrophil-Activating Factor (NAF) Produced by Human Monocytes},
  author={Alfred Ing Grad Walz and Paola Peveri and Heinrich Aschauer and Beatrice Dewald and Marco Baggiolini},
  year={1989}
}
Neutrophils are the main cellular elements of antimicrobial defense and acute inflammation. Their activity depends largely on the release of cytotoxic, tissue-damaging, and cell-activating products. A variety of stimulatory molecules of different origin are known to condition neutrophil activity in inflamed tissues. Among the best-characterized ones are N-formyl-methionyl peptides (e.g., fMLP) related to bacterial products (Showell et al. 1976), C5a formed upon complement activation (Fernandez… CONTINUE READING