Structure and Function of Cationic Amino Acid Transporters (CATs)

@article{Closs2006StructureAF,
  title={Structure and Function of Cationic Amino Acid Transporters (CATs)},
  author={Ellen Ildicho Closs and J.-P. Boissel and Alice Habermeier and Alexander Rotmann},
  journal={The Journal of Membrane Biology},
  year={2006},
  volume={213},
  pages={67-77}
}
The CAT proteins (CAT for cationic amino acid transporter) are amongst the first mammalian amino acid transporters identified on the molecular level and seem to be the major entry path for cationic amino acids in most cells. However, CAT proteins mediate also efflux of their substrates and thus may also deplete cells from cationic amino acids under certain circumstances. The CAT proteins form a subfamily of the solute carrier family 7 (SLC7) that consists of four confirmed transport proteins… CONTINUE READING

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