Structure and Dynamics of Interphase Chromosomes

@article{Rosa2008StructureAD,
  title={Structure and Dynamics of Interphase Chromosomes},
  author={Angelo Rosa and Ralf Everaers},
  journal={PLoS Computational Biology},
  year={2008},
  volume={4},
  pages={214 - 330}
}
During interphase chromosomes decondense, but fluorescent in situ hybridization experiments reveal the existence of distinct territories occupied by individual chromosomes inside the nuclei of most eukaryotic cells. We use computer simulations to show that the existence and stability of territories is a kinetic effect that can be explained without invoking… CONTINUE READING