Structure and Anticipatory Movements of the S6 Gate in K v Channels

Abstract

Potassium channels are a diverse family of membrane proteins that in humans are encoded by 75 distinct genes. The ion conduction pores in these channels are well conserved, supporting remarkable ion throughput rates (10 6 –10 7 s 1 ) in the face of exquisite selectivity for their namesake ion. Although some potassium channels are always open, more typically… (More)

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