Structure-activity relationships of three differently substituted 2,7,12,17-tetrakis-(β-methoxyethyl) porphycene derivatives in vitro

@article{Scherer2004StructureactivityRO,
  title={Structure-activity relationships of three differently substituted 2,7,12,17-tetrakis-(β-methoxyethyl) porphycene derivatives in vitro},
  author={Kathrin Scherer and Christoph Abels and Wolfgang B{\"a}umler and G{\"u}nther Ackermann and R.-M. Szeimies},
  journal={Archives of Dermatological Research},
  year={2004},
  volume={295},
  pages={535-541}
}
The subcellular localization, efficacy and photooxidative mechanism of three new photosensitizing porphycenes (HexoTMPn, PeloTMPn, CpoTMPn) for photodynamic therapy with different substituents at position 9 of the tetrapyrrole macrocycle were investigated in vitro using different human skin-derived cell lines (HaCaT, SCL I, SCL II) with the aim of… CONTINUE READING