Structure-activity relationships of chromogranin A in cell adhesion. Identification of an adhesion site for fibroblasts and smooth muscle cells.

Abstract

Previous studies showed that chromogranin A (CgA), a glycoprotein stored and co-released with various hormones by neuroendocrine cells and neurons, can modulate cell adhesion. We have investigated the structure-activity relationships of CgA using fibroblasts and coronary artery smooth muscle cells in adhesion assays. A recombinant CgA fragment 1-78 and a… (More)

Topics

Cite this paper

@article{Ratti2000StructureactivityRO, title={Structure-activity relationships of chromogranin A in cell adhesion. Identification of an adhesion site for fibroblasts and smooth muscle cells.}, author={S. Ratti and Flavio Curnis and Renato Longhi and Barbara Colombo and Anna Maria Gasparri and Fulvio Magni and E. Manera and Marie-H{\'e}l{\`e}ne Metz-Boutigue and Angelo Corti}, journal={The Journal of biological chemistry}, year={2000}, volume={275 38}, pages={29257-63} }