Corpus ID: 9908844

Structure-activity relationship studies of phenoxypropanolamine derivatives for beta 3-adrenergic activity.

@article{Ahmed2002StructureactivityRS,
  title={Structure-activity relationship studies of phenoxypropanolamine derivatives for beta 3-adrenergic activity.},
  author={Maruf Ahmed and Yoko Hanaoka and T. Nagatomo},
  journal={Nihon yakurigaku zasshi. Folia pharmacologica Japonica},
  year={2002},
  volume={120 1},
  pages={
          112P-113P
        }
}
In this study, some compounds of phenoxypropanolamine (SWR-0342SA) derivatives were found to possess beta 3-adrenoceptor (beta 3-AR) agonistic activity. Addition and deletion of the substituents on phenoxyacetate, chain length variation between two aromatic rings, conversion of phenoxypropanolamine to phenylethanolamine, insertion of double bonds and another ether group in the side chain between two phenyl rings in SWR-0342SA derivatives resulted in novel phenoxypropanolamine and… Expand
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