Structure-activity relationship of lipid core peptide-based Group A Streptococcus vaccine candidates.

Abstract

Infection with Group A Streptococcus (GAS) can result in a range of different illnesses, some of which are fatal. Currently, our efforts to develop a vaccine against GAS focuses on the lipid core peptide (LCP) system, a subunit vaccine containing a lipoamino acid (LAA) moiety which allows the stimulation of systemic antibody activity. In the present study… (More)
DOI: 10.1016/j.bmc.2016.03.063

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