Structure-activity relationship of alginate oligosaccharides in the induction of cytokine production from RAW264.7 cells.

@article{Iwamoto2005StructureactivityRO,
  title={Structure-activity relationship of alginate oligosaccharides in the induction of cytokine production from RAW264.7 cells.},
  author={Mami Iwamoto and Maki Kurachi and Takuji Nakashima and Daekyung Kim and Kenichi Yamaguchi and Tatsuya Oda and Yoshiko Iwamoto and Tsuyoshi Muramatsu},
  journal={FEBS letters},
  year={2005},
  volume={579 20},
  pages={4423-9}
}
Guluronate and mannuronate oligomers with various degree of polymerization were prepared from polyguluronate (PG) and polymannuronate (PM) with an alginate lyase from a Pseudoalteromonas sp., and their activities to induce cytokine secretion from mouse macrophage cell line RAW264.7 cells were examined. Enzymatically depolymerized unsaturated alginate… CONTINUE READING