Structure-activity relationship between the hydrophobicity of alkali metal salts of warfarin [3-(alpha-acetonyl-benzyl)-4-hydroxycoumarin] and the effectiveness of the taste response to these salts in mice.

@article{Ohnishi1995StructureactivityRB,
  title={Structure-activity relationship between the hydrophobicity of alkali metal salts of warfarin [3-(alpha-acetonyl-benzyl)-4-hydroxycoumarin] and the effectiveness of the taste response to these salts in mice.},
  author={Motoko Ohnishi and Ryoichi Sugawara and Tomonobu Kusano},
  journal={Bioscience, biotechnology, and biochemistry},
  year={1995},
  volume={59 6},
  pages={995-1001}
}
The taste responses to five alkali metal salts of warfarin, aqueous rodenticides, in laboratory mice were observed at a short measurement time of 20 min by the two-bottle preference test using a licking time monitoring system newly developed. It was made clear that the order of taste avoidance to the warfarin salts was as follows: cesium salt > rubidium salt > lithium salt > sodium salt > potassium salt. The relationship between the hydrophobicity of the warfarin salts and the effectiveness of… CONTINUE READING

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