Structure-Related Oxidative Damage in Rat Brain After Acute and Chronic Electroshock

  title={Structure-Related Oxidative Damage in Rat Brain After Acute and Chronic Electroshock},
  author={Tatiana Barichello and Fernanda Bonatto and Fabiano Rosa Agostinho and Adalisa Reinke and Jos{\'e} Cl{\'a}udio Fonseca Moreira and Felipe Dal-Pizzol and Ivan A. Izquierdo and Jo{\~a}o Quevedo},
  journal={Neurochemical Research},
The role of oxidative stress in electroconvulsive therapy–related effects is not well studied. The purpose of this study was to determine oxidative stress parameters in several brain structures after a single electroconvulsive seizure or multiple electroconvulsive seizures. Rats were given either a single electroconvulsive shock or a series of eight electroconvulsive shocks. Brain regions were isolated, and levels of oxidative stress in the brain tissue (cortex, hippocampus, striatum and… CONTINUE READING