Structure Of Hæemoglobin: A Three-Dimensional Fourier Synthesis of Reduced Human Haemoglobin at 5.5 Å Resolution

@article{Muirhead1963StructureOH,
  title={Structure Of H{\ae}emoglobin: A Three-Dimensional Fourier Synthesis of Reduced Human Haemoglobin at 5.5 Å Resolution},
  author={Hilary Muirhead and Max Ferdinand Perutz},
  journal={Nature},
  year={1963},
  volume={199},
  pages={633-638}
}
Structure Of Haeemoglobin: A Three-Dimensional Fourier Synthesis of Reduced Human Haemoglobin at 5.5 A Resolution 
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272 Citations
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Background Citations
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272 Citations

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References

SHOWING 1-10 OF 20 REFERENCES

Structure of Hæmoglobin: A Three-Dimensional Fourier Synthesis at 5.5-Å. Resolution, Obtained by X-Ray Analysis

Electron Spin Resonance in Myoglobin and Hæmoglobin: Orientation of the Hæm Group in Myoglobin and its Relation to the Polypeptide Chain Direction

Electron Spin Resonance in Myoglobin and Haemoglobin: Orientation of the Haem Group in Myoglobin and its Relation to the Polypeptide Chain Direction

The structure of haemoglobin VIII. A three-dimensional Fourier synthesis at 5.5 Å resolution: determination of the phase angles

Determination of the phase angles of a crystalline protein requires a series of isomorphous heavy-atom compounds, with heavy atoms attached to different sites on the protein molecule. The asymmetric…

The Structure of haemoglobin - VII. Determination of phase angles in the non-centrosymmetric [100] zone

  • D. Blow
  • Physics
    Proceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences
  • 1958
In the last paper in this series a Fourier projection down the [010] axis of horse haemoglobin was given (Bragg & Perutz 1954). This projection was centrosymmetric. As a first step towards the…

Some relations between structure and function in hemoglobin

Structure of Myoglobin: A Three-Dimensional Fourier Synthesis at 2 Å. Resolution

The reaction of normal adult human haemoglobin with heavy-metal reagents.

This work was done during the tenure of a British Council Scholarship (1957-59) and a grant from the Consejo Nacional de Investigaciones Cientificas y T6cnicas, (Buenos Aires, Argentina) (1959-60).…

The interaction of bromthymol blue with hemoglobin and its effect on the oxygen equilibrium.

Allosteric proteins and cellular control systems.

The single isomorphous replacement method

1195 and refinement was usually complete after ten to fifteen cycles. The refined values of the parameters compared well with the Rossmann programme values, except for the effective atomic numbers,…