Structure-Based Mechanism of Oleate Hydratase from Elizabethkingia meningoseptica

  title={Structure-Based Mechanism of Oleate Hydratase from Elizabethkingia meningoseptica},
  author={Matthias Engleder and Tea Pavkov-Keller and Anita Emmerstorfer and Altijana Hromic and Sabine Schrempf and Georg Steinkellner and Tamara Wriessnegger and E. von Leitner and Gernot A. Strohmeier and Iwona Kaluzna and Daniel Mink and Martin Sch{\"u}rmann and Silvia Wallner and Peter Macheroux and Karl Gruber and Harald Pichler},
  booktitle={Chembiochem : a European journal of chemical biology},
Hydratases provide access to secondary and tertiary alcohols by regio- and/or stereospecifically adding water to carbon-carbon double bonds. Thereby, hydroxy groups are introduced without the need for costly cofactor recycling, and that makes this approach highly interesting on an industrial scale. Here we present the first crystal structure of a recombinant oleate hydratase originating from Elizabethkingia meningoseptica in the presence of flavin adenine dinucleotide (FAD). A structure-based… CONTINUE READING
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Accepted article published:June 15, 2015 Final article published:J uly 14

Accepted article published:June 15, 2015 Final article published:J uly 14 • 2015


A Hiseni, I W. C E Arends, L G Otten
ChemCatChem • 2015

J. Biosci. Bioeng

M Ta Keuchi, S Kishino, +3 authors J Ogawa
J. Biosci. Bioeng • 2015


Manuscript • 2015

Angew.C hem. Int. Ed

J.-W Ong, E.-Y J Eon, +4 authors J Park
Angew.C hem. Int. Ed • 2013

Appl. Microbiol.Biotechnol

B.-N Kim, Y.-C Joo, Y.-S Kim, K.-R Kim, D.-K Oh
Appl. Microbiol.Biotechnol • 2012


Y.-C Joo, K.-W J Eong, +3 authors D.-K Oh
Biochimie • 2012

Hemmi in Handbook of Flavoproteins:O xidases,D ehydrogenases and Related Systems

Walterd e Gruyter • 2012

J. Biotechnol

Y.-C Joo, E.-S Seo, +3 authors D.-K Oh
J. Biotechnol • 2012

Biotechnol. Lett

B.-N Kim, S.-J Yeom, D.-K Oh
Biotechnol. Lett • 2011