Structure—Activity Relationships of Dopamine Receptor Agonists

@inproceedings{Kaiser1984StructureActivityRO,
  title={Structure—Activity Relationships of Dopamine Receptor Agonists},
  author={C. Kaiser},
  year={1984}
}
Dopamine (DA*), which is chemically defined as β-(3,4-dihydroxyphenyl) ethylamine, 3-hydroxytyramine, or 5-(2-aminoethyl)-1,2-benzenediol, was first synthesized in 1910 (Mannich and Jacobsohn, 1910). At that time it was classified as a sympathomimetic amine because only its epinephrinelike actions were known (Barger and Dale, 1910). Although its formation from L-Tyr via L-DOPA was recognized (Blaschko, 1939; Holtz, 1939), DA was not identified in the mammalian organism and shown to have… Expand
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