Structure–activity relationships of synthetic cannabinoid designer drug RCS-4 and its regioisomers and C4 homologues

@article{Banister2015StructureactivityRO,
  title={Structure–activity relationships of synthetic cannabinoid designer drug RCS-4 and its regioisomers and C4 homologues},
  author={Samuel D. Banister and Jordyn M. Stuart and Trent Conroy and Mitchell Longworth and Madhura Manohar and Corinne Beinat and Shane M. Wilkinson and Richard C. Kevin and David E. Hibbs and Michelle Glass and Mark Connor and Iain S. McGregor and Michael Kassiou},
  journal={Forensic Toxicology},
  year={2015},
  volume={33},
  pages={355-366}
}
RCS-4 [(4-methoxyphenyl)-1-yl-(1-pentyl-1H-indol-3-yl)methanone] represents the first of several N-alkyl-3-(methoxybenzoyl)indoles identified by forensic scientists as synthetic cannabinoid (SC) designer drugs. Despite the detection of RCS-4 and several analogues (RCS-2, RCS-3, RCS-2-C4, RCS-3-C4, and RCS-4-C4) in products intended for human consumption, relatively little is known about this class of cannabinoids. The synthesis of all regioisomers of RCS-4 and their C4 homologues is described… 
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