Structure‐based classification of FAD binding sites: A comparative study of structural alignment tools

  title={Structure‐based classification of FAD binding sites: A comparative study of structural alignment tools},
  author={Leonardo D. Garma and Milagros Medina and Andr{\'e} H. Juffer},
  journal={Proteins: Structure},
A total of six different structural alignment tools (TM‐Align, TriangleMatch, CLICK, ProBis, SiteEngine and GA‐SI) were assessed for their ability to perform two particular tasks: (i) discriminating FAD (flavin adenine dinucleotide) from non‐FAD binding sites, and (ii) performing an all‐to‐all comparison on a set of 883 FAD binding sites for the purpose of classifying them. For the first task, the consistency of each alignment method was evaluated, showing that every method is able to… 

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