Structure, function, and regulation of the kilB locus of promiscuous plasmid RK2.

@article{Thomson1993StructureFA,
  title={Structure, function, and regulation of the kilB locus of promiscuous plasmid RK2.},
  author={V J Thomson and Oliver S. Jovanovic and Robert F. Pohlman and Charlie Chang and David H. Figurski},
  journal={Journal of bacteriology},
  year={1993},
  volume={175 8},
  pages={
          2423-35
        }
}
The kil-kor regulon of the self-transmissible, broad-host-range plasmid RK2 is a unique network with eight coregulated operons. Among the genes encoded by the kil-kor regulon are trfA, which encodes the replication initiator, and several kil loci (kilA, kilB, kilC, and kilE), each of which is lethal to the host cell in the absence of appropriate negative regulatory elements encoded by the korA, korB, korC, and korE determinants. We have proposed that the functions of the kil loci are related to… CONTINUE READING