Structure, function, and regulation of the interleukin-2 receptor and identification of a novel immune activation gene.

Abstract

This chapter is divided into two sections, the first dealing with a novel immune activation gene, denoted Act-2. This gene encodes a secreted protein that may represent a new cytokine. The Act-2 protein shares significant homology with proteins in two related families of small secreted proteins. Act-2 is rapidly synthesized by activated T cells, B cells and… (More)

Topics

Cite this paper

@article{Leonard1990StructureFA, title={Structure, function, and regulation of the interleukin-2 receptor and identification of a novel immune activation gene.}, author={W. J. Leonard and James R. Gnarra and Melissa Napolitano and Michal Sharon}, journal={Philosophical transactions of the Royal Society of London. Series B, Biological sciences}, year={1990}, volume={327 1239}, pages={187-92} }