Structure, formation and role of cartilage canals in the developing bone.

@article{Blumer2008StructureFA,
  title={Structure, formation and role of cartilage canals in the developing bone.},
  author={Michael J. F. Blumer and Stefano Longato and H. -W. Fritsch},
  journal={Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft},
  year={2008},
  volume={190 4},
  pages={305-15}
}
In the long bones, endochondral bone formation proceeds via the development of a diaphyseal primary ossification centre (POC) and an epiphyseal secondary ossification centre (SOC). The growth plate, the essential structure for longitudinal bone growth, is located between these two sites of ossification. Basically, endochondral bone development depends upon neovascularization, and the early generation of vascularized cartilage canals is an initial event, clearly preceding the formation of the… CONTINUE READING

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