Structure, expression, and chromosomal assignment of the human gene encoding nuclear respiratory factor 1.

@article{Gopalakrishnan1995StructureEA,
  title={Structure, expression, and chromosomal assignment of the human gene encoding nuclear respiratory factor 1.},
  author={Lakshmi Gopalakrishnan and Richard C. Scarpulla},
  journal={The Journal of biological chemistry},
  year={1995},
  volume={270 30},
  pages={18019-25}
}
Nuclear respiratory factor 1 (NRF-1) is a transcription factor that acts on nuclear genes encoding respiratory subunits and components of the mitochondrial transcription and replication machinery. Here we describe the isolation and characterization of the human gene encoding NRF-1. The human genomic sequences detected with NRF-1 cDNA probes at high stringency are all contained within seven overlapping recombinant lambda clones. The NRF-1 gene encompassed by these recombinants spans… CONTINUE READING

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