Structure, distribution and physiological functions of ghrelin in fish.

  title={Structure, distribution and physiological functions of ghrelin in fish.},
  author={Suraj Unniappan and Richard Ector Peter},
  journal={Comparative biochemistry and physiology. Part A, Molecular & integrative physiology},
  volume={140 4},
Ghrelin was originally purified and characterized in rats and humans as the first identified endogenous ligand of the growth hormone secretagogue receptor. In mammals, ghrelin is mainly produced in the stomach, with minor levels of ghrelin present in the brain and various other tissues. Ghrelin is involved in the regulation of many physiological functions including the regulation of growth hormone secretion and food intake in mammals. The gene and peptide structures of ghrelin have been… CONTINUE READING

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