Structural variation of the human genome.

  title={Structural variation of the human genome.},
  author={Andrew J. Sharp and Ze Cheng and Evan E. Eichler},
  journal={Annual review of genomics and human genetics},
There is growing appreciation that the human genome contains significant numbers of structural rearrangements, such as insertions, deletions, inversions, and large tandem repeats. Recent studies have defined approximately 5% of the human genome as structurally variant in the normal population, involving more than 800 independent genes. We present a detailed review of the various structural rearrangements identified to date in humans, with particular reference to their influence on human… CONTINUE READING
128 Extracted Citations
139 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 128 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 139 references

Similar Papers

Loading similar papers…