Structural trees for protein superfamilies.

  title={Structural trees for protein superfamilies.},
  author={Alexander V Efimov},
  volume={28 2},
Structural trees for large protein superfamilies, such as beta proteins with the aligned beta sheet packing, beta proteins with the orthogonal packing of alpha helices, two-layer and three-layer alpha/beta proteins, have been constructed. The structural motifs having unique overall folds and a unique handedness are taken as root structures of the trees. The larger protein structures of each superfamily are obtained by a stepwise addition of alpha helices and/or beta strands to the corresponding… CONTINUE READING

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