Structural transitions and elasticity from torque measurements on DNA

@article{Bryant2003StructuralTA,
  title={Structural transitions and elasticity from torque measurements on DNA},
  author={Zev Bryant and Michael D. Stone and J. V. Gore and Steven R. B. Smith and Nicholas R. Cozzarelli and C. Bustamante},
  journal={Nature},
  year={2003},
  volume={424},
  pages={338-341}
}
Knowledge of the elastic properties of DNA is required to understand the structural dynamics of cellular processes such as replication and transcription. Measurements of force and extension on single molecules of DNA have allowed direct determination of the molecule's mechanical properties, provided rigorous tests of theories of polymer elasticity, revealed unforeseen structural transitions induced by mechanical stresses, and established an experimental and conceptual framework for mechanical… CONTINUE READING

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