Structural study on lipid A and the O-specific polysaccharide of the lipopolysaccharide from a clinical isolate of Bacteroides vulgatus from a patient with Crohn's disease.

@article{Hashimoto2002StructuralSO,
  title={Structural study on lipid A and the O-specific polysaccharide of the lipopolysaccharide from a clinical isolate of Bacteroides vulgatus from a patient with Crohn's disease.},
  author={Masahito Hashimoto and Fumiko Kirikae and Taeko Dohi and Seizi Adachi and Shoichi Kusumoto and Yasuo Suda and Tsuyoshi Fujita and Hideo Naoki and Teruo Kirikae},
  journal={European journal of biochemistry},
  year={2002},
  volume={269 15},
  pages={3715-21}
}
Bacteroides vulgatus has been shown to be involved in the aggravation of colitis. Previously, we separated two potent virulence factors, capsular polysaccharide (CPS) and lipopolysaccharide (LPS), from a clinical isolate of B. vulgatus and characterized the structure of CPS. In this study, we elucidated the structures of O-antigen polysaccharide (OPS) and lipid A in the LPS. LPS was subjected to weak acid hydrolysis to produce the lipid A fraction and polysaccharide fraction. Lipid A was… CONTINUE READING