Structural study of copper(I)-bleomycin

@article{Lehmann2004StructuralSO,
  title={Structural study of copper(I)-bleomycin},
  author={T. Lehmann},
  journal={JBIC Journal of Biological Inorganic Chemistry},
  year={2004},
  volume={9},
  pages={323-334}
}
  • T. Lehmann
  • Published 2004
  • Chemistry, Medicine
  • JBIC Journal of Biological Inorganic Chemistry
  • Previous NMR studies on Cu(I)-bleomycin have suggested that this adduct has a geometry distinct from Fe(II)BLM. The coordination chemistry of this bleomycin derivative has been investigated through the extension of the NMR data reported previously, and the use of molecular dynamics calculations. The data collected from the NMR experiments support the coordination to the metal center of the primary and secondary amines in β-aminoalanine and the pyrimidine ring. The detection in the NMR spectra… CONTINUE READING
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    References

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