Structural studies on the murine Ia alloantigens. IV. NH2-terminal sequence analysis of allelic products of the I-A and I-E/C subregions.

Abstract

Murine Ia alloantigens encoded by the I-A and I-E/C subregions were isolated from radiolabeled splenic lysates and examined by NH2-terminal sequence analysis. Haplotype-associated sequence variation was detected in the beta, but not alpha, subunits of both the A and E/C alloantigens. The A beta-polypeptides from k and b haplotypes show four differences in… (More)

Topics

  • Presentations referencing similar topics