Structural studies on adenoviruses.

  title={Structural studies on adenoviruses.},
  author={Carmen San Mart{\'i}n and Roger M. Burnett},
  journal={Current topics in microbiology and immunology},
The adenovirus genome encodes more than 40 proteins, of which 11 combine with the viral DNA to form an icosahedral capsid of approximately 150 MDa molecular weight and approximately 900 A in diameter. This chapter reviews the information that structural biology techniques have provided about the adenovirus proteins and capsid. The structures of two capsid proteins (hexon and fiber) and two non-structural polypeptides (DNA-binding protein and protease) have been solved by X-ray crystallography… CONTINUE READING


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