Structural studies of the Ca(2+) regulatory domain of Drosophila Na(+)/Ca (2+) exchanger CALX.

Abstract

CALX, the NCX homolog in Drosophila, involves in light-mediated Ca(2+) homeostasis in sensory neuronal cells. CALX exhibits a unique negative Ca(2+) regulatory property mediated by Ca2+ binding at its intracellular regulatory domain. Our structural studies of individual CBD1 or CBD2 domain reveal that CBD1 is the only Ca(2+) binding domain in CALX. Crystal… (More)
DOI: 10.1007/978-1-4614-4756-6_6

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@article{Zheng2013StructuralSO, title={Structural studies of the Ca(2+) regulatory domain of Drosophila Na(+)/Ca (2+) exchanger CALX.}, author={Lei Zheng and Mousheng Wu and Shuilong Tong}, journal={Advances in experimental medicine and biology}, year={2013}, volume={961}, pages={55-63} }