Structural studies of a human hybrid immunoglobulin

@article{Werner2005StructuralSO,
  title={Structural studies of a human hybrid immunoglobulin},
  author={Barbara G. Werner and Arthur Steinberg},
  journal={Immunogenetics},
  year={2005},
  volume={1},
  pages={254-271}
}
The structure of an hypothesized hybrid or “Lepore-type” IgG contained in the serum of donor 2904 was investigated. Previous immunological studies suggested that this serum contained IgG with aγ3-γ1 hybrid heavy chain consisting of aγ3 Fd portion and aγ1 Fc. Structural studies have now shown that the carboxyl terminal end of the 2904 hybrid IgG, including… CONTINUE READING