Structural stability and sustained release of protein from a multilayer nanofiber/nanoparticle composite.

Abstract

The cellular microenvironment can be engineered through the utilization of various nano-patterns and matrix-loaded bioactive molecules. In this study, a multilayer system of electrospun scaffold containing chitosan nanoparticles was introduced to overcome the common problems of instability and burst release of proteins from nanofibrous scaffolds. Bovine… (More)
DOI: 10.1016/j.ijbiomac.2015.01.051

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