Structural requirements of the mRNA for intracistronic translation initiation of the enterobacterial infB gene.

@article{Laursen2002StructuralRO,
  title={Structural requirements of the mRNA for intracistronic translation initiation of the enterobacterial infB gene.},
  author={Brian Laursen and S\oren A de A Steffensen and Jakob Hedegaard and Juan Manuel Palacios Moreno and Kim Mortensen and Hans Uffe Sperling-Petersen},
  journal={Genes to cells : devoted to molecular & cellular mechanisms},
  year={2002},
  volume={7 9},
  pages={901-10}
}
BACKGROUND The gene infB encodes the prokaryotic translation initiation factor IF2, a central macromolecular component in the formation of the ribosomal 70S initiation complex. In Escherichia coli, infB encodes three forms of IF2: IF2alpha, IF2beta and IF2gamma. The expression of IF2beta and IF2gamma is a tandem translation from intact infB mRNA and not merely a translation of post-transcriptionally truncated mRNA. The molecular mechanism responsible for the ribosomal recognition of the two… CONTINUE READING

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