Structural requirements and mechanism of the pressor activity of Leu-Val-Val-hemorphin-7, a fragment of hemoglobin beta-chain in rats.

@article{Moisan1998StructuralRA,
  title={Structural requirements and mechanism of the pressor activity of Leu-Val-Val-hemorphin-7, a fragment of hemoglobin beta-chain in rats.},
  author={Steve Moisan and Natasha Harvey and Genevi{\`e}ve Beaudry and P Forzani and Kenneth E. Burhop and Guy Drapeau and Frank Rioux},
  journal={Peptides},
  year={1998},
  volume={19 1},
  pages={119-31}
}
A rat blood pressure assay was used to perform a structure-activity relationship study (SAR) of Leu-Val-Val-hemorphin-7 (LVV-H7), a fragment of hemoglobin (Hb) beta-chain, elucidate the mechanisms of its cardiovascular effects, and test its potential involvement in the pressor activity of diaspirin crosslinked Hb (DCLHb), a recently developed Hb-based… CONTINUE READING