Structural rearrangements in the membrane penetration protein of a non-enveloped virus


Non-enveloped virus particles (those that lack a lipid-bilayer membrane) must breach the membrane of a target host cell to gain access to its cytoplasm. So far, the molecular mechanism of this membrane penetration step has resisted structural analysis. The spike protein VP4 is a principal component in the entry apparatus of rotavirus, a non-enveloped virus… (More)
DOI: 10.1038/nature02836


4 Figures and Tables

Slides referencing similar topics