Structural properties of a soluble bioactive precursor for transforming growth factor-alpha.

Abstract

The precursor for transforming growth factor-alpha, proTGF-alpha, is synthesized as an integral membrane glycoprotein with the mature TGF-alpha sequence located in the extracellular domain. Retrovirally transformed rat embryo fibroblasts (FeSV-Fre cells) expressing the endogenous proTGF-alpha gene release and accumulate in the medium mature TGF-alpha as… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.