Structural plasticity underlies experience-dependent functional plasticity of cortical circuits.

Abstract

The stabilization of new spines in the barrel cortex is enhanced after whisker trimming, but its relationship to experience-dependent plasticity is unclear. Here we show that in wild-type mice, whisker potentiation and spine stabilization are most pronounced for layer 5 neurons at the border between spared and deprived barrel columns. In homozygote… (More)
DOI: 10.1523/JNEUROSCI.6403-09.2010

Topics

4 Figures and Tables

Cite this paper

@article{Wilbrecht2010StructuralPU, title={Structural plasticity underlies experience-dependent functional plasticity of cortical circuits.}, author={Linda Wilbrecht and Anthony Holtmaat and Nick F Wright and Kevin Fox and Karel Svoboda}, journal={The Journal of neuroscience : the official journal of the Society for Neuroscience}, year={2010}, volume={30 14}, pages={4927-32} }