Structural plasticity of helical nanotubes based on coiled-coil assemblies.

  title={Structural plasticity of helical nanotubes based on coiled-coil assemblies.},
  author={Edward H. Egelman and Chunfu Xu and Frank DiMaio and Elizabeth L Magnotti and Charles Modlin and Xiong Wen Yu and Elizabeth R Wright and David P. Baker and Vincent P Conticello},
  volume={23 2},
Numerous instances can be seen in evolution in which protein quaternary structures have diverged while the sequences of the building blocks have remained fairly conserved. However, the path through which such divergence has taken place is usually not known. We have designed two synthetic 29-residue α-helical peptides, based on the coiled-coil structural motif, that spontaneously self-assemble into helical nanotubes in vitro. Using electron cryomicroscopy with a newly available direct electron… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS
11 Citations
50 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 11 extracted citations


Publications referenced by this paper.
Showing 1-10 of 50 references

Similar Papers

Loading similar papers…