Structural plasticity of dendritic spines

  title={Structural plasticity of dendritic spines},
  author={Shengxiang Zhang and Jiangbi Wang and Lei Wang},
  journal={Frontiers in Biology},
Dendritic spines are the major targets of excitatory synaptic input. They exist in a wide variety of shapes and sizes, from thin to mushroom-shaped to stubby. One of the striking characteristics of dendritic spines is their motile nature. Spines can undergo various structural modifications such as changes in density, shape, size, and motility. During development, spines are highly dynamic and many spines are formed and eliminated. As animals mature, most spines become stable and the vast… CONTINUE READING