Structural plasticity in actin and tubulin polymer dynamics.


Actin filaments and microtubules polymerize and depolymerize by adding and removing subunits at polymer ends, and these dynamics drive cytoplasmic organization, cell division, and cell motility. Since Wegner proposed the treadmilling theory for actin in 1976, it has largely been assumed that the chemical state of the bound nucleotide determines the rates of… (More)
DOI: 10.1126/science.1168823


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@article{Kueh2009StructuralPI, title={Structural plasticity in actin and tubulin polymer dynamics.}, author={Hao Yuan Kueh and Timothy J Mitchison}, journal={Science}, year={2009}, volume={325 5943}, pages={960-3} }