Structural patterns in globular proteins

@article{Levitt1976StructuralPI,
  title={Structural patterns in globular proteins},
  author={Michael Levitt and Cyrus Chothia},
  journal={Nature},
  year={1976},
  volume={261},
  pages={552-558}
}
A simple diagrammatic representation has been used to show the arrangement of α helices and β sheets in 31 globular proteins, which are classified into four clearly separated classes. The observed arrangements are significantly non-random in that pieces of secondary structure adjacent in sequence along the polypeptide chain are also often in contact in three dimensions. 
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