Structural organization of the pFra virulence-associated plasmid of rhamnose-positive Yersinia pestis.

@article{Golubov2004StructuralOO,
  title={Structural organization of the pFra virulence-associated plasmid of rhamnose-positive Yersinia pestis.},
  author={Andrey Golubov and Heinrich Neubauer and Christina Noelting and Juergen Heesemann and Alexander Rakin},
  journal={Infection and immunity},
  year={2004},
  volume={72 10},
  pages={5613-21}
}
The 137,036-bp plasmid pG8786 from rhamnose-positive Yersinia pestis G8786 isolated from the high mountainous Caucasian plague focus in Georgia is an enlarged form of the pFra virulence-associated plasmid containing genes for synthesis of the antigen fraction 1 and phospholipase D. In addition to the completely conserved genes of the pFra backbone, pG8786 contains two large regions consisting of 4,642 and 32,617 bp, designated regions 1 and 2, respectively. Region 1 retains a larger part of… CONTINUE READING

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