Structural organization of the human MS4A gene cluster on Chromosome 11q12

  title={Structural organization of the human MS4A gene cluster on Chromosome 11q12},
  author={Yinghua Liang and Thomas R Buckley and Lili Tu and Scott D. Langdon and Thomas F. Tedder},
CD20, the high-affinity IgE receptor β chain (FcεRIβ), and HTm4 are structurally related cell surface proteins expressed by hematopoietic cells. Recently, 16 novel human and mouse genes were identified that encode new members of this nascent protein family that we have named the membrane-spanning 4A gene family, with at least 12 subgroups (MS4A1–MS4A12). In the current study, we identified three additional human MS4A genes: MS4A4E, MS4A6E, and MS4A10. All family members have at least four… CONTINUE READING

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