Structural organization of rat CD1 typifies evolutionarily conserved CD1D class genes

@article{Katabami1998StructuralOO,
  title={Structural organization of rat CD1 typifies evolutionarily conserved CD1D class genes},
  author={Shigeo Katabami and Akihiro Matsuura and Hong-zhi Chen and Kohzoh Imai and Kokichi Kikuchi},
  journal={Immunogenetics},
  year={1998},
  volume={48},
  pages={22-31}
}
 The non-major histocompatibility complex (MHC)-encoded CD1 family has recently emerged as a new antigen-presenting system that is distinct from either MHC class I or class II molecules. In the present study, we determined the genomic structure of the rat CD1 locus. It was extremely similar to mouse CD1 genes, especially to CD1D1. The 5′ flanking region of the CD1 gene contained the binding motifs for two cytokine-inducible transcription factors, NF-IL2-A and NF-IL6. Some regulatory elements… CONTINUE READING
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CD1: from structure to function

  • F. Calabi, C. Y. Yu, A. G. Caroline, C. A. Bilsland, C. Milstein
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