Structural organization and unusual codon usage in the DNA polymerase gene from herpes simplex virus type 1.

@article{Hall1986StructuralOA,
  title={Structural organization and unusual codon usage in the DNA polymerase gene from herpes simplex virus type 1.},
  author={Jennifer D. Hall and J S Gibbs and Donald M Coen and David W. Mount},
  journal={DNA},
  year={1986},
  volume={5 4},
  pages={
          281-8
        }
}
We have analyzed the protein and nucleic acid sequences of the DNA polymerase from herpes simplex virus type 1 (HSV-1) to provide insight into the expression and possible structure of this enzyme. Extensive similarity between the amino acid sequence and that of the Epstein Barr virus DNA polymerase is reported. We describe probable structural similarities between these proteins and the use of these similarities to define structural and functional domains within the polymerase. Analysis of base… CONTINUE READING

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