Structural neuroplasticity following T5 spinal cord transection: increased cardiac sympathetic innervation density and SPN arborization.

@article{Lujan2010StructuralNF,
  title={Structural neuroplasticity following T5 spinal cord transection: increased cardiac sympathetic innervation density and SPN arborization.},
  author={Heidi L. Lujan and Gurunanthan Palani and Stephen E DiCarlo},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2010},
  volume={299 4},
  pages={R985-95}
}
When the spinal cord is injured at or below thoracic level 5 (T5), cardiovascular control is markedly unbalanced as the heart and blood vessels innervated by upper thoracic segments remain under brain stem control, whereas the vasculature of the lower body is affected by unregulated spinal reflexes. Importantly, the regulation of heart rate and cardiac function is abnormal after spinal cord injury (SCI) at T5 because sympathetic outflow to the heart is increased. An increase in tonic… CONTINUE READING
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