Structural molecular components of septate junctions in cnidarians point to the origin of epithelial junctions in eukaryotes.

@article{Ganot2015StructuralMC,
  title={Structural molecular components of septate junctions in cnidarians point to the origin of epithelial junctions in eukaryotes.},
  author={Philippe Ganot and Didier Zoccola and {\'E}ric Tambutt{\'e} and Christian R. Voolstra and Manuel Aranda and Denis Allemand and Sylvie Tambutt{\'e}},
  journal={Molecular biology and evolution},
  year={2015},
  volume={32 1},
  pages={44-62}
}
Septate junctions (SJs) insure barrier properties and control paracellular diffusion of solutes across epithelia in invertebrates. However, the origin and evolution of their molecular constituents in Metazoa have not been firmly established. Here, we investigated the genomes of early branching metazoan representatives to reconstruct the phylogeny of the molecular components of SJs. Although Claudins and SJ cytoplasmic adaptor components appeared successively throughout metazoan evolution, the… CONTINUE READING
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