Structural modulation of salt-resistant rat-liver lipase alters the relative phospholipase and triacylglycerol hydrolase activities.

@article{Persoon1987StructuralMO,
  title={Structural modulation of salt-resistant rat-liver lipase alters the relative phospholipase and triacylglycerol hydrolase activities.},
  author={N. L. Persoon and W. C. Hülsmann and H. Jansen},
  journal={Biochimica et biophysica acta},
  year={1987},
  volume={917 1},
  pages={
          186-93
        }
}
This paper demonstrates that structural modification of the heparin-releasable salt-resistant lipase of rat liver (liver lipase) alters its relative capacity to hydrolyze phospholipid and triacylglycerol emulsions. Enzymatic activities were modified by immunoinhibition and proteolysis and by selective amino acid agents. Binding of three different monoclonal antibodies resulted in a lower extent of inhibition of phospholipase than of triacylglycerol hydrolase activity. Degradation of the enzyme… Expand
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