Structural modification of the NH2 terminus of nerve growth factor. Purification and characterization of beta-nerve growth factor endopeptidase.


Nerve growth factor (NGF) is partially modified at its NH2 terminus during purification from mouse submaxillary gland. The significance of the cleavage of a histidine/methionine bond to produce an octapeptide from the NH2 terminus of PNGF is not yet understood. This study is concerned with the purification and characterization of the endopeptidase… (More)


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